Laboratory Services
ALK for NSCLC (Anaplastic lymphoma kinase)
Print this pageUpdated Test Information:
| Test Description |
ALK for NSCLC (Anaplastic lymphoma kinase)
|
|
|---|---|---|
| Synonym(s) |
ALK, NSCLC |
|
| General Information |
Probes: ALK (2p23) Disease(s): ALK, Non-small cell lung carcinoma (NSCLC) |
|
| Specimen Requirements |
Formalin fixed paraffin embedded (FFPE) tissue blocks or |
|
| Additional Processing Details |
Transport to the testing lab at room temp is acceptable. Do not allow sample to overheat. Use cold pack for transport, making sure cold pack is not in direct contact with specimen |
|
| Required Information |
Complete the Incyte Diagnostics hematology requisition with the patient's demographics and relevant clinical history. Label the specimen containers with patient's full name, second unique identifier, and specimen site/source. |
|
| Unacceptable Specimen Conditions |
Specimen containers without two (2) patient identifiers, specimens submitted on non-positively charged slides, paraffin blocks that have been overheated or frozen, specimens without a H&E slide, slides or paraffin blocks with no tissue remaining, Samples fixed in fixative other than 10% neutral buffered formalin. |
|
| Department (code) |
FISH |
|
| Methodology |
Fluorescence in-Situ Hybridization (FISH) |
|
| Estimated TAT |
4-7 working days from receipt |
|
| Testing Schedule |
Monday-Friday |
|
| Retention |
Blocks:10 years |
|
| CPT Code(s) |
88377x1 manual |
|
| Additional Information |
Clinical Significance: ALK gene rearrangements are found in 3-5% of non-small cell lung carcinoma (NSCLC). |
