Laboratory Services
AML (Acute myeloid leukemia) FISH Panel (Acute Promyelocytic Leukemia (APL))
Print this pageUpdated Test Information:
| Test Description |
AML (Acute myeloid leukemia) FISH Panel (Acute Promyelocytic Leukemia (APL))
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|---|---|---|
| Synonym(s) |
AML, APL |
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| General Information |
Probes: PML/RARA t(15;17), CBFB (inv(16), MLL (11q23), D7S486/CEP7, D20S108/CEP8, and RUNX1/RUNX1T1 t(8;21) (probes may be ordered separately) Disease(s): Acute myeloid leukemia (AML), Acute Promyelocytic Leukemia (APL) |
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| Specimen Requirements |
Bone Marrow Aspirate and Peripheral Blood |
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| Additional Processing Details |
Transport to the testing lab at room temp is acceptable. Do not allow sample to overheat or freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen |
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| Required Information |
Complete the Incyte Diagnostics hematology requisition with the patient's demographics and relevant clinical history. Label the specimen containers with patient's full name, second unique identifier, and specimen site/source. Please provide a copy of the patient's complete blood count (CBC) report |
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| Unacceptable Specimen Conditions |
Specimen containers without two (2) patient identifiers, specimens submitted in inappropriate collection media, frozen specimens. |
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| Department (code) |
FISH |
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| Methodology |
Fluorescence in-Situ Hybridization (FISH) |
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| Estimated TAT |
3-5 working days from receipt, can be ordered as a STAT result 24-48 hrs from receipt. |
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| Testing Schedule |
Monday-Friday |
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| Retention |
7 days after release of final report |
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| CPT Code(s) |
88377x6 manual |
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| Additional Information |
Clinical Significance: The AML panel identifies the most frequent cytogenetic abnormalities associated with favorable, intermediate, and poor risk AML/APL. |
