Laboratory Services

PML/RARA FISH Probe, t(15;17), Acute myeloid leukemia (AML), Acute Promyelocytic Leukemia (APL)

Name: Incyte Diagnostics
Address: 13103 E Mansfield Ave, Spokane Valley, Washington, 99216, USA
Telephone: +1-

Updated Test Information:

Test Description	PML/RARA FISH Probe, t(15;17), Acute myeloid leukemia (AML), Acute Promyelocytic Leukemia (APL)
Synonym(s)	AML, APL, t(15;17)
General Information	Probes: PML/RARA t(15;17) Disease(s): Acute myeloid leukemia (AML), Acute Promyelocytic Leukemia (APL)
Specimen Requirements	Bone Marrow Aspirate and Peripheral Blood 2-5 mL Sodium Heparin tube (preferred) EDTA tube (acceptable) Fixed-cell pellet from cytogenetic analysis slides with metaphase and/or interphase nuclei. (If sending slides please send at least 6 slides for testing)
Additional Processing Details	Transport to the testing lab at room temp is acceptable. Do not allow sample to overheat or freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen
Required Information	Complete the Incyte Diagnostics hematology requisition with the patient's demographics and relevant clinical history. Label the specimen containers with patient's full name, second unique identifier, and specimen site/source. Please provide a copy of the patient's complete blood count (CBC) report.
Unacceptable Specimen Conditions	Specimen containers without two (2) patient identifiers, specimens submitted in inappropriate collection media, frozen specimens.
Department (code)	FISH
Methodology	Fluorescence in-Situ Hybridization (FISH)
Estimated TAT	3-5 working days from receipt, can be ordered as a STAT result 24-48 hrs. from receipt.
Testing Schedule	Monday-Friday, Monday-Sunday if ordered as a STAT
Retention	7 days after release of final report
CPT Code(s)	88377x1 manual
Additional Information	Clinical Significance: The AML panel identifies the most frequent cytogenetic abnormalities associated with favorable, intermediate, and poor risk AML/AP If Flow Cytometry studies are also being ordered, it is preferable to submit an EDTA (purple top) tube specifically for Flow Cytometry. if only one tube can be submitted, please submit one sodium heparin (green top) tube for both FISH and Flow Cytometry studies.